Tryptophan Photodynamic Therapy
Photodynamic therapy (PDT) has been used as a treatment for non-melanoma skin cancers and pre-cancers such as actinic keratosis, squamous cell carcinoma in situ and basal cell carcinoma. It has also been used effectively as a treatment for acne. Nowadays, there are many studies that demonstrate the value of PDT for cosmetic uses as a photorejuvenation treatment. It provides excellent efficacy with high tolerability.
Until recently, the two photosensitizing agents used for the treatment were 5-alpha-amino levulinic acid (ALA) and the methyl ester of ALA. The substance is applied, allowed to “incubate” on the skin and is then activated with blue or red light. Typically the skin will be red and tender after the treatment. Riboflavin (vitamin B2) and Tryptophan have been introduced as a promising new photosensitizer complex for photodynamic therapy. Both Riboflavin and Tryptophan are naturally occurring substances. Tryptophan is a naturally occurring essential amino acid and riboflavin is vitamin B2. The typical side effects seen with ALA are significantly less pronounced with this form of PDT. Riboflavin with blue light activates tryptophan and forms radicals that react with water to create reactive oxygen species (ROS) – free radicals which then destroy the affected cells or in the case of acne – the bacteria and the sebaceous gland that cause the problem.
Typically you will require 3-4 treatment sessions to achieve the desired effect.
Tryptophan Photodynamic Therapy Before & After Photos
Models may not be actual patients of Abby Medical Laser Centre
